1.

MATTERS OF ADMINISTRATION

1.1

Welcome and apologies

1.2

Minutes and recommendations of the 189^th MARC meeting

1.3

Declarations of potential competing interests

2.

MATTERS ARISING FROM THE NZ PHARMACOVIGILANCE CENTRE

2.1

CARM quarterly report

3.

PHARMACOVIGILANCE REPORTS

3.1

Matters referred to the MARC under section 36 of the Medicines Act 1981

3.1.1 Buccaline: referral to the Committee under section 36(2) of the Medicines Act 1981

3.2

Matters referred to the MARC by Medsafe

3.2.1 Opioids and serotonin syndrome

3.2.3 Prostaglandin associated periorbitopathy   

3.2.4 Methenamine benefit risk review

4.

MEDSAFE PHARMACOVIGILANCE ACTIVITIES

4.1

Report on standing agenda items

4.2

Medsafe pharmacovigilance activities

4.3

Prescriber Update

4.4

Quarterly summary of recent safety communications

5.

OTHER BUSINESS