1.

MATTERS OF ADMINISTRATION

1.1

Welcome and apologies

1.2

Minutes and recommendations of the 185th MARC meeting

1.3

Declarations of potential conflicts of interest

2.

MATTERS ARISING FROM THE NZ PHARMACOVIGILANCE CENTRE

2.1

CARM quarterly report

3.

PHARMACOVIGILANCE REPORTS

3.1

Matters referred to the MARC by Medsafe under section 36 of the Medicines Act 1981

3.1.1

Consideration of bufexamac-containing medicines under section 36 of the Medicines Act 1981

3.2

Matters referred to the MARC by Medsafe

3.2.1

Boron-containing excipients and fertility concerns

3.2.2

Misuse of stimulant laxatives

3.2.3

Options for minimising opioid abuse, misuse and dependence

4.

MEDSAFE PHARMACOVIGILANCE ACTIVITIES

4.1

Report on standing agenda items

4.2

Medsafe pharmacovigilance activities

4.3

Prescriber Update

4.4

Quarterly summary of recent safety communications