Committees

Agenda for the 180th meeting of the Medicines Adverse Reactions Committee to be held on Thursday 5 december 2019, at 9 am

1.	MATTERS OF ADMINISTRATION
1.1	Welcome and apologies
1.2	Minutes and recommendations of the 179th MARC meeting
1.3	Declarations of potential conflicts of interest
2.	MATTERS ARISING FROM THE NZ PHARMACOVIGILANCE CENTRE
2.1	CARM quarterly report
3.	PHARMACOVIGILANCE REPORTS
3.1	Matters referred to the MARC under section 36 of the Medicines Act 1981
	3.1.1 None
3.2	Matters referred to the MARC by Medsafe
	3.2.1 Pholcodine: benefit-risk review
	3.2.2 Direct oral anticoagulants and the risk of a rebound effect
	3.2.3 Cyproterone acetate and the risk of hepatic toxicity
	3.2.4 Potential drug-drug interaction between capecitabine and proton pump inhibitors
4.	MEDSAFE PHARMACOVIGILANCE ACTIVITIES
4.1	Report on standing agenda items
4.2	Medsafe pharmacovigilance activities
4.3	Prescriber Update
4.4	Quarterly summary of recent safety communications
5.	OTHER BUSINESS