1.

MATTERS OF ADMINISTRATION

1.1

Welcome and apologies

1.2

Minutes and recommendations of the 169th MARC meeting

1.3

Declarations of potential conflicts of interest

2.

MEDSAFE PHARMACOVIGILANCE ACTIVITIES

2.1

Report on standing agenda items

2.2

Medsafe pharmacovigilance activities

2.3

Prescriber Update

2.4

Quarterly summary of recent safety communications

3.

PHARMACOVIGILANCE REPORTS

3.1

Matters referred to the MARC under section 36 of the Medicines Act 1981

3.2

Matters referred to the MARC by Medsafe

3.2.1

Safety of antibiotic ear drops in children with grommets

3.2.2

NSAIDs and spontaneous abortion

3.2.3

The risk of haemorrhage from concomitant use of statins and dabigatran

3.2.4

Gadolinium based contrast agents and accumulation in brain tissue

4.

MATTERS ARISING FROM THE NZ PHARMACOVIGILANCE CENTRE

4.1

CARM quarterly report

5.

OTHER BUSINESS

5.1

Therapeutic products regulation project - Update